In a research paper published in the jouranl Neuron on December 20,scientists have demonstrated that the symptoms of Fragile X can be reversed in mice that were genetically engineered to manifest the symptoms found in humans. Fragile X syndrome is associated with developmental disorders such as learning disorders,attention deficit disorder and vulnerability to seizures. A third of those with the syndrome are autistic.
The paper is co-authored by seven scientists,including two are bangalore based : Sumantra Chattarji, Professor,National Centre for Biological Sciences; and B.S.Shankaranarayana Rao,Associate Professor,NIMHANS.
The paper discusses the "Major therapeutic implications" of this finding and possibilities of developing drugs to treat the disorder. " We have known for a long time now that individuals with the Fragile X syndrome have very low concentrations of an important protein,FMRP ( Fragile X Mental Retardation Protein ), which is instrumental in the developmental of the brain and in the forming of synaptic connections "explains Prof.Chattarji.